Madueke, Lewis-Skelly And Odegaard To Start | 4-3-3 Arsenal Predicted Lineup Vs Brentford

Arsenal will welcome Brentford at the Emirates Stadium on Wednesday night as they look to secure all three points at home in the Premier League. The Gunners were held to a 1-1 draw away at Chelsea recently, so they would be eager to get back to winning ways in the league in midweek.

Mikel Arteta will set his side up in a 4-3-3 formation and is expected to make some changes to his first XI for this game. Noni Madueke, Myles Lewis-Skelly and Martin Odegaard could all play from the start of this contest versus the Bees.

4-3-3 Arsenal Predicted Lineup To Face Brentford

Defence

David Raya will operate in between the sticks for the Gunners after conceding one goal in his last appearance. Cristhian Mosquera will function alongside Piero Hincapie at the heart of the Arsenal backline as they hope to keep a good shape at the back during the 90 minutes.

Jurrien Timber will continue to operate as the right-back, while Myles Lewis-Skelly gets a chance to impress on the other side as the left-back. Both of them will get the freedom to go forward and join in on the attack at every chance they can get.

Ben White and Riccardo Calafiori will provide cover for the defensive positions on the bench.

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Arsenal
LONDON, ENGLAND – NOVEMBER 30: David Raya of Arsenal reacts during the Premier League match between Chelsea and Arsenal at Stamford Bridge on November 30, 2025 in London, England. (Photo by Mike Hewitt/Getty Images)

Midfield

Declan Rice, Martin Zubimendi and Martin Odegaard will make up Arsenal’s midfield. Their main job would be to retain possession well at the centre of the park and engineer some decent chances for their teammates up top.

Christian Norgaard, Eberechi Eze and Ethan Nwaneri will be named on the bench as they await their chance to influence the game in the second 45 minutes if needed.

Attack

Noni Madueke will try to catch the eye as the left-sided wide player, while Bukayo Saka hopes to make a difference from the right flank. Both of them will look to use their pace to get in behind the Brentford backline.

Viktor Gyokeres will lead the charge for the North London club up top. He has to figure out a way to be a constant menace in and around the opponent’s penalty area.

Mikel Merino and Gabriel Martinelli will have to be content with a place on the bench and might come on to make an impact in the latter stages of the contest if required.