Midfield
Oriol Romeu is likely to rest in this fixture with Harrison Reed taking up the central midfield role.
Pierre-Emile Höjbjerg seems to improve with every passing game and Puel is likely to start with him against Arsenal.
In the defensive midfield role, Dutch international Jordy Clasie is expected to get a nod.
James Ward-Prowse has also been a regular in Southampton’s EFL run and we expect him to remain on the bench.
Attack
Shane Long is finally expected to get a start in this match as managers often tend to gauge their player’s fitness through these matches.
Wenger is also expected to do the same with injury returned Lucas Perez. Spanish international Jay Rodriguez is expected to start on the left flank with Morroco international Sofiane Boufal on the right.
Puel will surely be resting his starting attacking trio of Nathan Redmond, Charlie Austin, and Josh Sims. Wales International Isgrove is expected to remain on the bench.